Prof. Wan-Uk KIM (Korea)

Education :
MD, School of Medicine, Catholic University of Korea, Feb 1991
PhD, School of Medicine, Catholic University of Korea, Aug 2002

Career :
1997-02 Instructor of Internal Medicine (Rheumatology), Catholic University of Korea, Seoul
2003-07 Assistant Professor of Internal Medicine, Catholic University of Korea, Seoul
2007-08 Visiting Scholar of Internal Medicine, Yale University, New Haven, CT
2007- Associate Professor of Internal Medicine, Catholic University of Korea, Seoul
2009- Director, Research Institute of Immunobiology, Catholic University of Korea

Major Interests
Pathogenesis of rheumatoid arthritis
Angiogenesis
Synoviocyte biology

Recent Representative Original Research

  1. Kong JS, Yoo SA, Kim JW, Yang SP, Chae CB, Cho CS, Kim WU. Anti-neuropilin-1 peptide inhibits synoviocyte survival, angiogenesis, and experimental arthritis. Arthritis Rheum 2010;62:179-90 (Highlight Issue)
  2. Kong JS, Yoo SA, Kim HS, Kim HA, Ryu SH, Chung YJ, Cho CS, Kim WU. Sulforaphane, a naturally occurring isothiocyanate, inhibits synovial hyperplasia, rheumatoid T cell activation and experimental arthritis in mice. Arthritis Rheum 2010;62:159-70.
  3. Yoo SA, Youn HJ, Kim HS, Chae CB, De Falco S, Cho CS, Kim WU. Role of placental growth factor and its receptor Flt-1 in rheumatoid inflammation: A link between angiogenesis and inflammation. Arthritis Rheum 2009;60:345-54 (Highlight Issue)
  4. Yoo SA, Park BH, Yoon HJ, Lee JY, Song JH, Kim HA, Cho CS, Kim WU. Calcineurin modulates the catabolic and anabolic activity of chondrocyte, and participates in the progression of experimental osteoarthritis. Arthritis Rheum, 2007;56:803-9.
  5. Yoo SA, Park BH, Park GS, Koh HS, Lee MS, Ryu SH, Miyazawa K, Park SH, Cho CS, Kim WU. Calcineurin is expressed and plays a critical role in inflammatory arthritis. J Immunol, 2006;177:2681-90 (Issue of 15th August 15).
  6. Lee MS, Yoo SA, Cho CS, Suh PG, Kim WU and Ryu SH. (2006) "Serum amyloid A binding to formyl peptide receptor-like 1 induces synovial hyperplasia and angiogenesis" J Immunol, 2006;177:5585-94 (Issue of 15th October; corresponding author).
  7. Kim WU, Kang SS,Yoo SA, Hong KH, Bae DG, Lee MS, Hong SW, Chae CB, Cho CS. The interaction of VEGF165 with neuropilin-1 protects rheumatoid synoviocytes from apoptotic death by regulating Bcl-2 expression and Bax translocation. J. Immunol, 2006; 177:5727-35.
  8. Yoo SA, Kim HR, Ryoo JW, Cho CS, Bae DG, Chae CB, Kim WU. Arginine-rich Anti-Vascular Endothelial Growth Factor (anti-VEGF) Hexapeptide Inhibits Collagen-Induced Arthritis and VEGF-Stimulated Productions of Tumor Necrosis Factor-Ą and Interleukin-6 by Human Monocytes. J Immunol 2005;174:5846-5855.